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Data from a XENICAL and cyclosporine drug interaction study indicate a reduction in cyclosporine plasma levels when XENICAL was coadministered with cyclosporineThereforeXENICAL and cyclosporine should not be simultaneously coadministeredTo reduce the chance of a drug-drug interactioncyclosporine should be taken at least amantadine sulfate. 3 hours before or after XENICAL in patients taking both drugsIn additionin those patients whose cyclosporine levels are being measuredmore frequent monitoring should be considered.

Patients should be informed of potential risks which include lowered absorption of fat-soluble vitamins and potential liver injuryincreases in urinary oxalateand cholelithiasissee WARNINGS AND PRECAUTIONSTreatment with XENICAL may result in crestor online without prescripton. weight loss and improvement in obesity-related risk factors due to weight losssee Clinical Studies

This list is not completeOther drugs may interact with orlistatincluding prescription and over-the-counter medicinesvitaminsand herbal productsNot all possible interactions are listed in this medication guide.

Loss of virological control has been reported in HIV-infected patients taking orlistat concomitantly with antiretroviral drugs such as atazanavirritonavirtenofovir disoproxil fumarateemtricitabineand with the combinations lopinavir/ritonavir and emtricitabine/efavirenz/tenofovir disoproxil fumarateThe exact mechanism for this is unclearbut may include a drug-drug interaction that inhibits systemic absorption of the antiretroviral drugHIV RNA levels should be frequently monitored in patients who take XENICAL while being treated for HIV infectionIf there is a confirmed increase in HIV viral loadXENICAL should be discontinued.

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