Widespread multidrug resistance in escherichia coli has necessitated the reintroduction of older antibiotics, such as nitrofurantoin.

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It is not known if Nimotop crosses into human milkBecause many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medicationa choice should be made whether to stop nursing or stop the use of this medicationYour doctor and you will decide if the benefits outweigh the risk of using Nimotop.

You should seek advice from your doctor or pharmacist about taking this medicineThey can help you balance the risks and the benefits of this medicine during pregnancy.

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32 however the activity of nitrofurantoin is also ph dependent and mean inhibitory concentration rises sharply with increased ph above 6.