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Investigations into the mode of action of LASIX have utilized micropuncture studies in ratsstop flow experiments in dogs and various clearance studies in both humans and experimental animalsIt has been demonstrated that LASIX inhibits primarily the absorption of sodium and chloride not only in the proximal and distal tubules but also in the loop of HenleThe high degree of efficacy is largely due to the unique site of actionThe action on the distal tubule is independent of any inhibitory effect on carbonic anhydrase and aldosterone.

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use Lasix only for the indication prescribed.

In generaldose selection for the elderly patient should be cautioususually starting top 10 online viagra sites. at the low end of the dosing rangesee PRECAUTIONSGeriatric Use

In patients with hepatic cirrhosis and ascitesLASIX therapy is best initiated in the hospitalIn hepatic coma and in states of electrolyte depletiontherapy should not be instituted until the basic condition is improvedSudden alterations of fluid and electrolyte balance in patients with cirrhosis may precipitate hepatic comathereforestrict observation is necessary during the period of diuresisSupplemental potassium chloride andif requiredan aldosterone antagonist are helpful in preventing hypokalemia and metabolic alkalosis.

Oral LASIX may be used in adults for the treatment of hypertension alone or in combination with other antihypertensive agentsHypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with LASIX alone.

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